ALISKIREN – All About Drugs
ALISKIREN – All About Drugs
Decades-old renin inhibitors are still struggling to find a niche in antihypertensive therapy. A fleeting look at the old and the promising new molecules - ScienceDirect
ALISKIREN – All About Drugs
Luca BANFI, Università degli Studi di Genova, Genoa, UNIGE, Department of Chemistry and Industrial Chemistry
PDF) A New Synthetic Route Towards Aliskiren Intermediates
EP2075244A1 - New route to building block for making renin inhibitors - Google Patents
Total Synthesis of “Aliskiren”: The First Renin Inhibitor in Clinical Practice for Hypertension
Luca BANFI, Università degli Studi di Genova, Genoa, UNIGE, Department of Chemistry and Industrial Chemistry
Aliskiren: the first renin inhibitor for clinical treatment
PDF] Amide Bond Formation via Reversible, Carboxylic Acid-Promoted Lactone Aminolysis
Structural Modification of the P2' Position of 2,7-Dialkyl-Substituted 5(S)-Amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets
A Mixed-Ligand Approach Enables the Asymmetric Hydrogenation of an α-Isopropylcinnamic Acid en Route to the Renin Inhibitor Aliskiren